Download A Case Approach to Perioperative Drug-Drug Interactions by Catherine Marcucci, Michael P. Hutchens et al. (eds.) PDF

By Catherine Marcucci, Michael P. Hutchens et al. (eds.)

The prevalence of deleterious or perhaps deadly drug-drug interactions (DDIs) within the perioperative interval is not any longer a theoretical drawback yet a harrowing truth. A Case method of Perioperative Drug-Drug Interactions addresses the complicated realm of pharmacokinetic drug interactions in an easy-to-read quantity that features as either a finished medical reference and a casebook. The booklet offers a precis of the center techniques of drug interactions; an geared up, annotated presentation of the drug interactions such a lot proper to the perioperative clinician; and nearly 2 hundred case eventualities that spotlight particular drug interactions. This ebook fills a true void within the scientific literature and is priceless to anesthesiologists and surgeons, in addition to trainees in either specialties; extensive care employees, together with physicians, physician’s assistants, and nurses; and nurse practitioners who employees preoperative evaluate clinics.

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Kristin Ondecko Ligda MD and Erin A. Sullivan MD 883 199 Cold and Sick, Sick and Cold . . . . . . . . . . . . . . . . A. Murat Kaynar MD, MPH and Nikhil K. Bhatnagar MD 887 200 TPN (I): A Review and Two Interactions . . . . . . . . . . . Lavinia Kolarcyzk MD and Patrick J. Forte MD 891 xxx Contents 201 TPN (II): A Traumatic Case of Increased Metabolism . . . . . . Erica D. Wittwer MD, PhD, Wayne T. Nicholson MD, PharmD, MSc, and Juraj Sprung MD, PhD 895 202 Skin and Bones .

Brian D. Tompkins MD and Kirk Lalwani MD, FRCA, MCR 937 212 Pain on the Plane . . . . . . . . . . . . . . . . . . . . . Lei Wu MD and Kirk Lalwani MD, FRCA, MCR 941 213 Ca va, c’est Kava . . . . . . . . . . . . . . . . . . . . . Solina Tith MD and Kirk Lalwani MD, FRCA, MCR 945 214 Summertime and the Herbals Are Hot . . . . . . . . . . . . Jessica Miller MD, BM and Leelee Thames MD 949 215 Garlic I: More Than Just Bad Breath .

Clinically, the drug concentration is targeted for the therapeutic window through proper dosage, thereby maximizing therapeutic effects while minimizing adverse effects (Fig. 1). D. T. edu © Springer Science+Business Media New York 2015 C. Marcucci et al. 1007/978-1-4614-7495-1_2 9 10 Introduction to Drug–Drug Interactions Fig. 1 The relation of the therapeutic window of drug concentration to the therapeutic and adverse effects in the patient population. The ordinate is linear; the abscissa is logarithmic [Adapted from Blumenthal DK, Garrison JC.

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